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Tofranil is a tricyclic antidepressant that has been used to treat bed-wetting for about 30 years. How it works is not clear, but it is known to have a relaxing effect on the bladder, allowing the bladder to hold more urine comfortably.

Side effects of Tofranil tend to be rare with correct dosage but may include:

Note Tofranil can have toxic side effects if not taken as directed. Deaths have been attributed to accidental overdoses.

  • Nervousness
  • Anxiety
  • Constipation
  • Personality changes
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