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There are two groups of antipsychotics. Doctors call the older group of medications “first-generation,” “typical,” or “conventional” antipsychotics. Some common ones are:

The newer ones are called “second-generation,” or “atypical” antipsychotics. Examples of these medicines include:

Note: Clozapine is the only FDA approved medication for treating schizophrenia that is resistant to other treatments. It’s also indicated for decreasing thoughts of suicidal behaviors in those with schizophrenia who are at risk

  • Chlorpromazine (Thorazine)
  • Fluphenazine (Prolixin)
  • Haloperidol (Haldol)
  • Perphenazine (Trilafon)
  • Thioridazine (Mellaril)
  • Thiothixene (Navane)
  • Trifluoperazine (Stelazine)
  • Aripiprazole (Abilify)
  • Aripiprazole lauroxil (Aristada)
  • Asenapine (Saphris)
  • Brexpiprazole (Rexulti)
  • Cariprazine (Vraylar)
  • Clozapine (Clozaril)
  • Iloperidone (Fanapt)
  • Lurasidone (Latuda)
  • Olanzapine (Zyprexa)
  • Paliperidone  (Invega Sustenna)
  • Paliperidone palmitate (Invega Trinza)
  • Quetiapine (Seroquel)
  • Risperidone (Risperdal)
  • Ziprasidone (Geodon)
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