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Multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS) are different diseases with some similar features and symptoms.

They both:

They have some key differences, though. MS is an autoimmune disease that causes your body to attack itself. ALS, also called Lou Gehrig’s disease, is a nervous system disorder that wears away nerve cells in your brain and spinal cord. Both are treated differently.

  • Affect your muscles and your ability to move your body
  • Attack your brain and spinal cord
  • Have “sclerosis” in their name
  • Cause scarring or hardening around nerve cells
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