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There are many reasons why estrogen levels fall, including:

  • Hypogonadism
  • Hypopituitarism
  • Pregnancy failure (estriol)
  • Perimenopause and menopause (estradiol)
  • Polycystic ovarian syndrome (PCOS)
  • Anorexia nervosa (eating disorder)
  • Extreme exercise or training

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