Make the call if your symptoms don't disappear after you finish taking all your medicine as prescribed. See your doctor if you have four or more vaginal yeast infections in one year. Your doctor may call this “recurrent vulvovaginal candidiasis.” It’s not common, but if you have it, you may need to take an antifungal medication for up to six months. Frequent, repeated yeast infections can also be a sign of a resistant strain or more serious condition, including untreated diabetes. Also call your doctor or pharmacist if you have any questions about your prescription and how to take your medicine.