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There are reports that glucosamine may also reduce the effectiveness of certain drugs. So use caution when taking glucosamine if you take:

  • Acetaminophen (Tylenol)
  • Certain chemotherapy drugs, including doxorubicin (Adriamycin, Rubex), etoposide (Etopiside), and teniposide (Vumon)
  • Diabetes drugs, including glimepiride (Amaryl), glyburide (DiaBeta), insulin (NovoLog), pioglitazone (Actos), and rosiglitazone (Avandia)
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