A combination of treatment methods might raise your chances of quitting. For example, using both a nicotine patch and gum may be better than a patch alone. Other combination treatments that are helpful include behavioral therapy and nicotine replacement therapy; prescription medication used together a nicotine replacement therapy patch; and a nicotine replacement therapy patch and nicotine spray. The FDA hasn’t approved using 2 types of nicotine replacement therapies at the same time, so talk with your doctor first.