Gangrene is a serious medical condition that requires immediate medical treatment. While most people with dry gangrene recover fully with treatment, gangrene that involves an infection can be life-threatening. The sooner you get treatment, the better your chances of recovery. If you have ongoing and unexplained pain in any area in your body, fever, a wound that is slow to heal, or you notice a change in skin color, make an appointment to see your doctor right away or go to the emergency room.