Treatment is not fast and easy. Home treatment for hand warts, for instance, can take a few weeks up to a few months. Foot warts are challenging to treat because most of the wart lies below the skin surface. Even if a treatment is successful, the wart can reappear. If a wart is not bothersome, doctors say it can be left alone. Given time, the wart may disappear on its own, thanks to the immune system.