Two quick options that do not cause too much discomfort are freezing the skin wart with liquid nitrogen or burning it off. In some instances, your dermatologist will use laser to treat especially stubborn warts, although there is no evidence that this form of treatment works any better than other treatment options. Doctors may also use a chemical called cantharidin on the wart, which causes a blister to form beneath the growth. When the skin on the top of the blister dies, it contains part of the wart and can be removed. Other options include surgical removal of the wart and the injection or application of certain drugs that strengthen your immune system’s response to the wart.