Another treatment option for heavy sweating is injections of botulinum toxin A (Botox), the same medicine used for wrinkles. Botox is FDA-approved for treating excessive sweating of the underarms, but some doctors may also use it on the palms of the hands and soles of the feet.
Botox works by preventing the release of a chemical that signals the sweat glands to activate. You may need to have several Botox injections, but the results can last for almost a year.