Take medicine as instructed. Do this even if schizophrenia symptoms have gone away. Stopping medicine is the most common cause of relapses. How quickly this happens varies. It can be days, weeks, or months after stopping. Work closely with your doctor to find the lowest dose to control symptoms, as well as the best method and type of medication. For example, a once-a-month, long-acting antipsychotic given by a shot helps some people stay on track. Avoid alcohol and illegal drugs. They make symptoms worse and a relapse more likely. Friends and family members can help you find services that treat substance abuse problems.