As part of your rheumatoid arthritism (RA) treatment, your doctor will probably prescribe a nonsteroidal anti-inflammatory drug (NSAID). These medications reduce pain and inflammation, but don't slow down the disease's progression. So, if you have moderate to severe RA, you’ll probably also need to take other drugs to prevent further joint damage.
Over-the-counter NSAIDs include ibuprofen and naproxen. Most people with RA need a prescription NSAID, as they offer a higher dose with longer-lasting results and require fewer doses throughout the day.
There are many prescription NSAIDs that your doctor will consider. All of them carry a warning about the increased risk of heart attack and stroke. NSAIDs can also raise blood pressure and can cause stomach irritation, ulcers, and bleeding.
You and your doctor can weigh the benefits of NSAIDs against the potential risks. You may have to try a few different ones to find the one that’s right for you.