Doctors usually treat juveile rheumatoid arthritis with nonsteroidal anti-inflammatory drugs (NSAIDs) such as celecoxib (Celebrex), diclofenac (Voltaren), ibuprofen (Advil, Motrin), and naproxen (Aleve, Naprosyn). These help relieve fever, pain, and joint inflammation. They also sometimes prescribe corticosteroid medications like prednisone. These drugs lessen the immune response and help with inflammation.