1) Amelia, meromelia and micromelia
These anomalies of the limb are rare and mainly hereditary due to chromosomal abnormalities. However, as already discussed, thalidomide has been proved to be a teratogenic drug that causes gross limb deformities.
Amelia means absence of one or more of the limbs (in Greek melos = limb).
Meromelia is an anomaly in which parts of one or more limbs are missing. Sometimes the proximal segment of a limb is normal but the distal portion is missing; such condition is known as hemimelia. In another condition, called phocomelia, the proximal segments of the limbs are missing and the hands and feet are attached directly to the trunk like the flippers of a [ seal (in Greek phoke = seal)
Micromelia is an anomaly in which all segments of the limbs are present but much shorter than normal.