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If you have fibromyalgia, some drugs can ease the pain and help you sleep better:

  • Over-the-counter pain relievers, such as acetaminophen and naproxen.
  • Antidepressants. These medications can ease aches and fatigue. They can also help you get a better night's rest.
  • Anti-seizure medicines. Drugs that treat epilepsy can give you relief by making you less sensitive to pain.
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