Nonsteroidal anti-inflammatory drugs (NSAIDs) may raise your chances of a heart attack or stroke, especially if you take them in high doses.
You may also get an upset stomach if you take NSAIDs regularly. Sometimes they cause other serious problems, like painful ulcers or bleeding. If that happens, your doctor might give you another drug to protect your stomach while you take the NSAID. Celecoxib is safer for your stomach than others.