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Itchiness usually has a simple, common cause. In some cases, however, if it doesn’t go away, could be a sign of a serious illness, such as:

You might also start itching after the treatments for some of these illnesses. Kidney dialysis, chemotherapy, and radiation therapy have itching as a side effect.

  • Kidney disease
  • Liver disease
  • Thyroid problems
  • Certain cancers, particularly Hodgkin’s disease
  • Diabetes
  • Iron deficiency
  • HIV
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