Use an exfoliating acid. Applied to the skin, products with these acids work by weakening the bonds between skin cells. This causes the outer layer to shed, which softens and removes scales. You can buy creams, lotions, gels, ointments, foams, and shampoos with these acids. They’re available over the counter (OTC) or in stronger doses by prescription. Side effects include irritation, stinging, and burning.
Some exfoliating acids used to treat psoriasis include:
- Salicylic acid: Also found in acne medicines, it’s one of the most common treatments for psoriasis. By softening a protein in your skin called keratin, salicylic acid helps psoriasis scales come off faster. Make sure to follow your doctor’s orders when you apply it. If too much is absorbed into your body, it can cause health problems. You shouldn’t apply it to large areas of skin or leave it on for long periods of time -- and children shouldn’t use products that contain it at all.
- Alpha-hydroxy acids: This category includes glycolic and lactic acids. They may be as effective as salicylic acid, but gentler on the skin.
- Urea: This thins and moisturizes the skin.