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Sometimes, when a pathologist looks at the prostate cells under the microscope, they don't look cancerous, but they're not quite normal, either. These results are often reported as "suspicious" and fall into one of two categories, either atypical or prostatic intraepithelial neoplasia (PIN). PIN is often further divided into low grade and high grade. The significance of low-grade PIN in relation to prostate cancer remains unclear. Many men have it when they are young and never develop prostate cancer. Biopsy results that fall into either atypical or high-grade PIN are suspicious for the presence of prostate cancer in another portion of the gland. There is a 30% to 50% likelihood of finding prostate cancer in a later biopsy when high-grade PIN is initially discovered. For this reason, repeat biopsies are generally recommended.

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