Symptoms that may arise as pancreatic cancer progresses include: Significant weight loss accompanied by abdominal pain -- the most likely warning signs.
Vague but gradually worsening abdominal pain that may decrease when leaning forward and increase when lying down. Pain is often severe at night and may radiate to the lower back.
Digestive or bowel complaints such as diarrhea, constipation, gas pains, bloating, or belching.
Nausea, vomiting, and loss of appetite.
Jaundice, which is usually painless and is indicated by yellowish discoloration of the skin and eye whites, very dark urine, and light-colored stools.
Sudden onset of glucose tolerance disorder, such as diabetes.
Black or bloody stool, indicating bleeding from the digestive tract.
Overall weakness.
Enlarged liver and gallbladder.
Itching.
Blood clots in the legs.
Mental status changes, such as a new onset of depression.