Anticonvulsant and antidepressant drugs are often the first line of treatment. Some neuropathic pain studies suggest that NSAIDs (non-steroidal anti-inflammatory drugs) -- aspirin, ibuprofen, and naproxen -- may ease pain. Some people may need a stronger painkiller. Talk about the pros and cons of the medicine you take with your doctor. If you have another condition, such as diabetes, make sure it's under control. In hard-to-treat cases, you may need to see a pain specialist for electrical stimulation of the affected nerves.