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Nerve pain is caused by damage to the nerve. Some health conditions, drugs, and toxins that can cause it include:

  • Diabetes
  • Human immunodeficiency virus (HIV) infection
  • Celiac disease
  • Trauma
  • Amyloidosis
  • Fabry's disease
  • Medications, including B6 (pyridoxine), isoniazid, HIV drugs, or chemotherapy
  • Toxins, such as heavy alcohol use
  • Autoimmune conditions, such as lupus and vasculitis
  • Vitamin B12 deficiency
  • Some cancers, such as lymphoma or myeloma
  • Lyme disease

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