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Some medications can cause a buildup of gum tissue, a condition called "gingival overgrowth." Gum tissue becomes so swollen that it begins to grow over the teeth and could lead to gum disease. Medications that can cause this include:

Men are more likely to develop this side effect.

  • Phenytoin, a seizure medication
  • Cyclosporine, an immunosuppressant drug often used to prevent transplant rejection
  • Blood pressure medications called calcium channel blockers, which include nifedipine, verapamil, diltiazem, and amlodipine
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