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What medications are used to manage symptoms of multiple sclerosis?

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To target specific symptoms of multiple sclerosis, your doctor may recommend:

  • Muscle relaxants such as baclofen (Lioresal) and tizanidine (Zanaflex) or sedatives like clonazepam (Klonopin) and diazepam (Valium), for muscle stiffness and spasms
  • Amantadine (Symmetrel), armodafinil (Nuvigil), modafinil (Provogil), for fatigue
  • Antidepressants, such as bupropion (Wellbutrin), fluoxetine (Prozac), and sertraline (Zoloft), for depression
  • Oxybutynin (Ditropan) or tolterodine (Detrol), for bladder problems

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