You can take Baclofen as a pill or get a shot into an area of your spine called the intrathecal space, which is filled with the fluid that surrounds your spinal cord and nerve roots. This type of treatment, called intrathecal baclofen (ITB), can help people who have a hard time with side effects of the pill form. It delivers the drug right to the spinal cord, so it doesn’t circulate throughout the body first. You need only tiny doses for the drug to work, which keeps side effects to a minimum.