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A lack of feeling or a pins-and-needles sensation can be the first sign of the nerve damage from MS. It usually happens in the face, arms, or legs, and on one side of the body. It also tends to go away on its own.

Numbness and tingling can also come from a lack of blood flow or a pinched nerve, so think first if you slept in a funny position or sat without moving for a long time. Other conditions can lead to nerve damage, too: Carpal tunnel syndrome affects the wrist, while diabetic neuropathy can trigger numbness, tingling, or pain in the feet or hands.

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