The blood vessels are the part of the circulatory system, and microcirculation, that transports blood throughout the human body.[1] These vessels are designed to transport nutrients and oxygen to the tissues of the body. They also take waste and carbon dioxide and carry them away from the tissues and back to the heart. Blood vessels are needed to sustain life as all of the body’s tissues rely on their functionality.[2]There are three major types of blood vessels: the arteries, which carry the blood away from the heart; the capillaries, which enable the actual exchange of water and chemicals between the blood and the tissues; and the veins, which carry blood from the capillaries back toward the heart. The word vascular, meaning relating to the blood vessels, is derived from the Latin vas, meaning vessel. A few structures (such as cartilage and the lens of the eye) do not contain blood vessels and are labeled.
The arteries and veins have three layers. The middle layer is thicker in the arteries than it is in the veins:
The inner layer, tunica intima, is the thinnest layer. It is a single layer of flat cells (simple squamous epithelium) glued by a polysaccharide intercellular matrix, surrounded by a thin layer of subendothelial connective tissue interlaced with a number of circularly arranged elastic bands called the internal elastic lamina. A thin membrane of elastic fibers in the tunica intima run parallel to the vessel.
The middle layer tunica media is the thickest layer in arteries. It consists of circularly arranged elastic fiber, connective tissue, polysaccharide substances, the second and third layer are separated by another thick elastic band called external elastic lamina. The tunica media may (especially in arteries) be rich in vascular smooth muscle, which controls the caliber of the vessel. Veins don't have the external elastic lamina, but only an internal one. The tunica media is thicker in the arteries rather than the veins.
The outer layer is the tunica adventitia and the thickest layer in veins. It is entirely made of connective tissue. It also contains nerves that supply the vessel as well as nutrient capillaries (vasa vasorum) in the larger blood vessels.
Capillaries consist of little more than a layer of endothelium and occasional connective tissue.
When blood vessels connect to form a region of diffuse vascular supply it is called an anastomosis. Anastomoses provide critical alternative routes for blood to flow in case of blockages.
There is a layer of muscle surrounding the arteries and the veins which help contract and expand the vessels. This creates enough pressure for blood to be pumped around the body. Blood vessels are part of the circulatory system, together with the heart and the blood.
The biggest difference in the structure of arteries and veins is the presence of valves. Backflow of blood is prevented in arteries by the heart. However in veins, one-direction valves are used to prevent backflow as a result of a decrease in blood pressure as the blood passes through the circulatory system